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Tyrer-Cuzick Risk Assessment Calculator

This risk calculator asks questions about your personal and family history to determine the possibility of developing breast cancer. The results will display your 10-year risk and your lifetime risk score. The purpose of this tool is simply to inform you. Please consult with your physician should you have any questions about your risk for breast cancer or for guidance on options for breast cancer screening or genetic counseling.

The Tyrer-Cuzick model is not intended to assess the risk of women who have already been diagnosed with breast cancer.

Attention Clinical Users: This free calculator is for non-commercial, including non-clinical use. Such use would require a license. Learn more about our clinical risk assessment software.

Assess Breast Cancer Risk

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Tyrer-Cuzick Risk Model (IBIS Breast Cancer Risk Evaluation Tool)

This calculator uses the Tyrer-Cuzick or IBIS v8 risk assessment model.

*Note: Competing mortality is turned "ON" for consistency. Competing mortality is the possibility that one may die from causes other than breast cancer.

*Disclaimer: This information is not intended as a substitute for professional healthcare and is not intended to replace the evaluation of a healthcare professional. Always consult with a healthcare provider for advice concerning your health. Only your healthcare provider can determine if you have breast cancer. Do not disregard professional medical advice or delay seeking advice or treatment because of something you have read here.

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cancer historyMother

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cancer historyFather

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cancer historySisters

cancer historyDaughters

cancer historyBrother

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Do any of your brothers have a daughter with a history of breast or ovarian cancer?
Add Niece

cancer historyPaternal Grandmother

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cancer historyPaternal Aunts

cancer historyPaternal Half Sisters

cancer historyPaternal Uncle's Daughters

cancer historyMaternal Grandmother

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cancer historyMaternal Aunts

cancer historyMaternal Half Sisters

cancer historyMaternal Uncle's Daughters

Your Results

The results below are based on the IBIS risk assessment model. These results display your 10-year risk and your lifetime risk compared to the U.S. population average. Please consult with your physician should you have any questions about your risk for breast cancer or for guidance on options for breast cancer screening or genetic counseling.

IBIS Breast Cancer Risk Assessment Score

Personal 10-Year Risk

Population 10-Year Risk

Personal Lifetime Risk

Population Lifetime Risk

Based on the information provided, the patient’s estimated risk for developing invasive breast cancer over the next 10 years is . The U.S. population’s average 10-year risk is for women of the same age and race/ethnicity. Based on the information provided, the patient’s estimated risk for developing invasive breast cancer in her lifetime is . The U.S. population’s average lifetime risk is for women of the same age and race/ethnicity.

Note for medical professionals: This risk calculation is provided with competing mortality turned "ON" per recommendation from Brentnall & Cuzick in Risk Models for Breast Cancer and Their Validation. Having competing mortality "ON" can lower the overall lifetime risk value.

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Frequently Asked Questions

The risk calculator can determine the possibility of developing breast cancer within 10 years of your current age and lifetime. The purpose of this tool is to help you become informed and assist in how you should proceed for genetic counseling and testing.

Q1. What is the Tyrer-Cuzick model and how is it used for breast cancer risk assessment?

The Tyrer-Cuzick model, sometimes referred to as IBIS tool, provides a risk score that estimates the likelihood of a woman developing breast cancer in 10 years and over the course of her lifetime. The risk score is calculated using a variety of risk factors that include personal health history, as well as family history of cancers. The score is typically expressed as a percentage.

Q2. What are the risk factors used to calculate the Tyrer-Cuzick score?

The major risk factors are:

  • Age
  • Height
  • Weight
  • Age at menarche
  • Age at first delivery
  • Age at menopause
  • Breast density
  • Ashkenazi Jewish heritage
  • History of hormone use
  • Genetic testing results for BRCA 1 and BRCA 2
  • Number of daughters
  • Number of sisters & half sisters
  • Number of maternal aunts
  • Number of paternal aunts
  • Atypical breast biopsies, ie: ADH, ALH, LCIS
  • History of breast biopsy/surgery
  • Personal or family history of Breast cancer
  • Age cancer was diagnosed
  • Cancer in one breast or both breasts

Q3. What does it mean to have dense breast tissue, and why does it matter for my Tyrer-Cuzick risk score?

Breast cancer research and advances in risk assessment have shown that having dense breasts is a contributing factor in determining a woman’s risk of breast cancer. Dense breast tissue refers to the appearance of breast tissue on a mammogram and the makeup of supportive and fatty tissue in the breast. The more fatty tissue, the less dense the breast is. Dense breast are common and can be caused by simply being younger, having a lower body mass index, or taking hormone therapy for menopause; researchers are still studying why some women have dense breast and other do not. Non-dense tissue appears dark and transparent, whereas dense breast tissue appears as solid white area on a mammogram; the solid white area can make it hard for radiologists to accurately analyze the image with a mammogram, so your provider may recommend supplemental imaging, like a breast ultrasound or other recommendations, to ensure no cancers are missed. Having dense breast alone is not cause for concern, and you should speak with your doctor about your breast density and how it affects your risk status.

Q4. Why is it important for me to know my risk score?

Risk assessment can help breast centers tailor screening and follow up recommendations to ensure you are receiving the care you need. Risk assessment identifies women who are candidates for additional imaging, genetic counseling, genetic testing, and/or other specialized recommendations.

Q5. What is considered a high risk score for Tyrer-Cuzick?

Some facilities may have different guidelines, so you should check with your imaging provider, but generally:

  • Less than 15% is considered average risk
  • Between 15-19% is considered intermediate risk
  • Greater than 20% is considered high risk

Q6. Are there other risk models like Tyrer-Cuzick?

Yes, there are other risk models such as Gail/NCI, BRCAPRO, Claus, BCSC and more; however, Tyrer-Cuzick has been widely accepted as the most comprehensive risk model due to the more detailed data collection. Your facility may use one or more of the models together.

Q7. How can I have my risk score calculated?

While risk calculators and other tools exist online, it is best to speak with you doctor about having your risk score calculated. Learning you are high risk from an online calculator without guidance from your doctor may only cause unnecessary anxiety.

Q8. I am in the high risk category – does this mean I will definitely develop breast cancer?

No, being high risk just means that when statistically compared to other women, your chances are higher, sometimes only slightly higher. It is completely understandable to be concerned about your high risk status, but early detection is our best tool against breast cancer. By identifying your risk, your doctors can provide you with a personalized screening plan and/or risk reduction options.

Q9. I am in the high risk category – Is there anything I can do to reduce my risk of being diagnosed with breast cancer?

You should speak with your doctor about your specific circumstances to determine if there is anything you can do to lower your risk. In some cases, your doctor may recommend lifestyle changes, and in higher risk cases, there are risk lowering drugs and interventional surgery options. It is important, however, that your doctor make the appropriate recommendations.

Q10. I have already been diagnosed with breast cancer. Does risk assessment apply to me?

No, risk assessment does not apply to those over the age of 85 and those already diagnosed with breast cancer.

Q11. Are there any additional resources online to learn more about breast cancer risk assessment?

While your doctor and imaging providers are the best resources, here are a few sites that can provide you with more information until you speak to your doctors:

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